Article
Functional analysis of the Campylobacter jejuni N-linked protein glycosylation pathway.
Molecular microbiology - 1 Mar 2005
Linton Dennis, Dorrell Nick, Hitchen Paul G, Amber Saba, Karlyshev Andrey V, Morris Howard R, Dell Anne, Valvano Miguel A, Aebi Markus, Wren Brendan W
Abstract excerpt
We describe in this report the characterization of the recently discovered N-linked glycosylation locus of the human bacterial pathogen Campylobacter jejuni, the first such system found in a species from the domain Bacteria. We exploited the ability of this locus to function in Escherichia coli to demonstrate through mutational and structural analyses that variant glycan structures can be transferred onto protein...
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