Article
Crystal structure of the C-terminal globular domain of oligosaccharyltransferase from Archaeoglobus fulgidus at 1.75 Å resolution.
Biochemistry - 22 May 2012
Matsumoto Shunsuke, Igura Mayumi, Nyirenda James, Matsumoto Masaki, Yuzawa Satoru, Noda Nobuo, Inagaki Fuyuhiko, Kohda Daisuke
Abstract excerpt
Protein N-glycosylation occurs in the three domains of life. Oligosaccharyltransferase (OST) transfers glycan to asparagine in the N-glycosylation sequon. The catalytic subunit of OST is called STT3 in eukaryotes, AglB in archaea, and PglB in eubacteria. The genome of a hyperthermophilic archaeon, Archaeoglobus fulgidus, encodes three AglB paralogs. Two of them are the shortest AglBs across all domains of life....
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