Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A switch in regulatory T cells through farm exposure during immune maturation in childhood.

Allergy - 1 Apr 2017

Schröder P C, Illi S, Casaca V I, Lluis A, Böck A, Roduit C, Depner M, Frei R, Genuneit J, Pfefferle P I, Roponen M, Weber J, Braun-Fahrländer C, Riedler J, Dalphin J C, Pekkanen J, Lauener R, von Mutius E, Schaub B

Abstract excerpt

BACKGROUND: Farm exposure protects against development of allergies early in life. At 4.5 years, protection against asthma by farm-milk exposure was partially mediated by regulatory T cells (Tregs). The aim of this study was to investigate the critical time window of the 'asthma-protective' farm effect via Tregs during childhood immune maturation. METHODS: Tregs were assessed longitudinally at 4.5 and 6 years in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allergens
Share to Farms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunity

Share to Immunoglobulin E

Share to Lymphocyte Count

Share to Population Surveillance

Share to T-Lymphocyte Subsets

Share to T-Lymphocytes, Regulatory

Source

Identifiers

PMID: 27732759
DOI: 10.1111/all.13069

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A switch in regulatory T cells through farm exposure during immune maturation in childhood.PMID 27732759Read ↗

Longitudinal relationship of early life immunomodulatory T cell phenotype and function to development of allergic sensitization in an urban cohort.Semantic proximity Read ↗

Regulatory T Cells Developing Peri-Weaning Are Continually Required to Restrain Th2 Systemic Responses Later in Life.Semantic proximity Read ↗

Maternal allergic disease history affects childhood allergy development through impairment of neonatal regulatory T-cells.Semantic proximity Read ↗

Regulation of TH17 markers early in life through maternal farm exposure.Semantic proximity Read ↗

Integrating farm and air pollution studies in search for immunoregulatory mechanisms operating in protective and high‐risk environmentsSemantic proximity Read ↗

A Phenotypically Distinct Human Th2 Cell Subpopulation Is Associated With Development of Allergic Disorders in Infancy.Semantic proximity Read ↗

Childhood Immune Maturation and Allergy Development: Regulation by Maternal Immunity and Microbial ExposureSemantic proximity Read ↗

Immunological footprint: the development of a child's immune system in environments rich in microorganisms and parasitesSemantic proximity Read ↗

The farm effect, orSemantic proximity Read ↗

Role of early life immune regulation in asthma developmentSemantic proximity Read ↗

Prenatal and early-life exposures alter expression of innate immunity genes: the PASTURE cohort study.Semantic proximity Read ↗

Synchronization of mothers and offspring promotes tolerance and limits allergySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.