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Article

ApoA-I mutations, L202P and K131del, in HDL from heterozygotes with low HDL-C.

Proteomics. Clinical applications - 1 Apr 2014

Ljunggren Stefan, Levels Johannes H M, Turkina Maria V, Sundberg Sofie, Bochem Andrea E, Hovingh Kees, Holleboom Adriaan G, Lindahl Mats, Kuivenhoven Jan Albert, Karlsson Helen

Abstract excerpt

PURPOSE: Mutations in apolipoprotein A-I (apoA-I) may affect plasma high-density lipoprotein (HDL) cholesterol levels and the risk for cardiovascular disease but little is known about the presence and effects of circulating apoA-I variants. This study investigates whether the apoA-I mutations, apoA-I(L202P) and apoA-I(K131del) , are present on plasma HDL particles derived from heterozygote carriers and whether...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24273187
DOI: 10.1002/prca.201300014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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