Article
Apolipoprotein A-I deficiency. Biochemical and metabolic characteristics.
Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 1995
Ng D S, Vezina C, Wolever T S, Kuksis A, Hegele R A, Connelly P W
Abstract excerpt
Familial HDL deficiencies are associated with variable susceptibility to premature coronary heart disease, but the mechanism underlying this association remains poorly understood. Three homozygotes with isolated complete apo A-I deficiency caused by an autosomal codominant apo A-I Q[-2]X mutation...
Topics
- Apolipoprotein A-I
- Apolipoprotein A-II
- Apolipoproteins B
- Cholesterol
- Diterpenes
- Female
- Heterozygote
- Homozygote
- Humans
- Lipoproteins
- Lipoproteins, HDL
- Lipoproteins, LDL
- Male
- Mutation
- Phosphatidylcholine-Sterol O-Acyltransferase
- Phospholipids
- Retinyl Esters
- Triglycerides