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Article

Apolipoprotein A-I deficiency. Biochemical and metabolic characteristics.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 1995

Ng D S, Vezina C, Wolever T S, Kuksis A, Hegele R A, Connelly P W

Abstract excerpt

Familial HDL deficiencies are associated with variable susceptibility to premature coronary heart disease, but the mechanism underlying this association remains poorly understood. Three homozygotes with isolated complete apo A-I deficiency caused by an autosomal codominant apo A-I Q[-2]X mutation and one heterozygote developed coronary heart disease before age 40 years. We characterized the effects of this...

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Identifiers

PMID: 7489237
DOI: 10.1161/01.atv.15.12.2157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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