Article
Small, dense LDL and elevated apolipoprotein B are the common characteristics for the three major lipid phenotypes of familial combined hyperlipidemia.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2003
Ayyobi Amir F, McGladdery Sandra H, McNeely Marguerite J, Austin Melissa A, Motulsky Arno G, Brunzell John D
Abstract excerpt
OBJECTIVE: Familial combined hyperlipidemia (FCHL) is associated with variable lipid and lipoprotein phenotypes arbitrarily defined as type IIa, IIb, and IV based on plasma total cholesterol and triglyceride levels. This study sought to characterize consistent lipoprotein and lipid abnormalities across the 3 lipoprotein phenotypes in 62 patients with documented FCHL (IIa [n=14], IIb [n=19], and IV [n=29]) and 44...
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