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Article

Transactivating mutation of the MYOD1 gene is a frequent event in adult spindle cell rhabdomyosarcoma.

The Journal of pathology - 1 Feb 2014

Szuhai Karoly, de Jong Daniëlle, Leung Wai Yi, Fletcher Christopher D M, Hogendoorn Pancras C W

Abstract excerpt

Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children and adolescents, being characterized by expression of genes and morphological and ultrastructural features of sarcomeric differentiation. The spindle cell variant of rhabdomyosarcoma (spindle cell RMS) in adults has been defined as an entity, separated from embryonal rhabdomyosarcoma (ERMS), with unfavourable clinical outcome. So far, no...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24272621
DOI: 10.1002/path.4307

Genes

MYOD1
EML5
MYC
MYF5
MYF6
MYOG
NOTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Transactivating mutation of the MYOD1 gene is a frequent event in adult spindle cell rhabdomyosarcoma.PMID 24272621Read ↗

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