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Article

Cytogenetic and Molecular Study of an Adult Sclerosing Rhabdomyosarcoma of the Extremity: MYOD1-mutation and Clonal Evolution.

Cancer genomics & proteomics - 1 Jan 2000

Gorunova Ludmila, Bjerkehagen Bodil, Micci Francesca, Heim Sverre, Panagopoulos Ioannis

Abstract excerpt

BACKGROUND: Spindle cell/sclerosing rhabdomyosarcoma is a genomically heterogeneous, uncommon subtype of rhabdomyosarcoma, particularly rare in adults. Its MYOD1-mutant variant is aggressive irrespective of age. Cytogenetic data on spindle cell/sclerosing rhabdomyosarcoma are sparse and disparate. MATERIALS AND METHODS: Cytogenetic and molecular analyses were performed on an adult sclerosing rhabdomyosarcoma....

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Identifiers

PMID: 32859634
DOI: 10.21873/cgp.20212
PMCID: PMC7472446

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