Article
Association study of mitochondrial genetic polymorphisms in asthmatic children.
Mitochondrion - 1 Jan 2014
Flaquer Antònia, Heinzmann Andrea, Rospleszcz Susanne, Mailaparambil Beena, Dietrich Henriette, Strauch Konstantin, Grychtol Ruth
Abstract excerpt
It has been suggested that mitochondrial dysfunction plays a role in the pathogenesis of asthma. To test whether mitochondrial variants influence the risk of asthma, we analyzed 16,158 mtSNPs in a sample of 372 asthmatic children and 395 healthy children using the DNA pooling technique and genome wide association analysis. Stratified analysis by sex was performed to explain the differences observed between sexes...
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