Article
Next Generation Exome Sequencing of Pediatric Asthma Identifies Rare and Novel Variants in Candidate Genes.
Disease markers - 1 Jan 2021
Bogari Neda M, Amin Amr A, Rayes Husni H, Abdelmotelb Ahmed, Taher Mohiuddin M, Al-Allaf Faisal A, Bouazzaoui Abdellatif, O'Gorman Luke, Holloway John W
Abstract excerpt
Multiple genes have been implicated to have a role in asthma predisposition by association studies. Pediatric patients often manifest a more extensive form of this disease and a particularly severe disease course. It is likely that genetic predisposition could play a more substantial role in this group. This study is aimed at identifying the spectrum of rare and novel variation in known pediatric asthma...
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