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Article

Hydrocodone in postoperative personalized pain management: pro-drug or drug?

Clinica chimica acta; international journal of clinical chemistry - 15 Feb 2014

Stauble M Elaine, Moore Andrew W, Langman Loralie J, Boswell Mark V, Baumgartner Richard, McGee Suzanne, Metry Jonathan, Jortani Saeed A

Abstract excerpt

BACKGROUND: Genetic variations in enzymes that produce active metabolites from pro-drugs are well known. Such variability could account for some of the clinically observed differences in analgesia and side effects seen in postoperative patients. Using genotyping and quantitation of serum concentrations of hydrocodone and its metabolites, we sought to demonstrate the clinical effects of the metabolites of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24269714
DOI: 10.1016/j.cca.2013.11.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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