Article
Pharmacogenetics of opioids for the treatment of acute maternal pain during pregnancy and lactation.
Current drug metabolism - 1 Jul 2012
Madadi Parvaz, Avard Denise, Koren Gideon
Abstract excerpt
There have been an increasing number of clinical studies investigating the relationship between interindividual genetic variability and the safety and efficacy of opioid analgesics. Despite the widespread use of opioids in pregnant and lactating women for the treatment of acute pain, few studies have investigated the interplay of genetic factors and pregnancy-related physiological alterations in relation to...
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