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Article

Epigenetic inactivation of heparan sulfate (glucosamine) 3-O-sulfotransferase 2 in lung cancer and its role in tumorigenesis.

PloS one - 1 Jan 2013

Hwang Jung-Ah, Kim Yujin, Hong Seung-Hyun, Lee Jieun, Cho Yong Gu, Han Ji-Youn, Kim Young-Ho, Han Joungho, Shim Young Mog, Lee Yeon-Su, Kim Duk-Hwan

Abstract excerpt

BACKGROUND: This study was aimed at investigating the functional significance of heparan sulfate (glucosamine) 3-O-sulfotransferase 2 (HS3ST2) hypermethylation in non-small cell lung cancer (NSCLC). METHODOLOGY/ PRINCIPAL FINDINGS: HS3ST2 hypermethylation was characterized in six lung cancer cell lines, and its clinical significance was analyzed using 298 formalin-fixed paraffin-embedded tissues and 26...

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Identifiers

PMID: 24265783
DOI: 10.1371/journal.pone.0079634
PMCID: PMC3827134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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