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Diagnostic and prognostic impact of desmocollins in human lung cancer

21 Sept 2012

Abstract excerpt

OBJECTIVE: Desmosomes are intercellular junctions that confer strong cell-cell adhesion. Two main members of desmosomal cadherins, desmogleins (DSGs) and desmocollins (DSCs), are involved in carcinogenesis. However, their role in human lung cancer remained elusive. The aims of this study were to analyse the expression of DSCs and to evaluate their clinical application in lung cancer. METHODS: The expression of...

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PMID: 23002285
DOI: 10.1136/jclinpath-2011-200630

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