Article
Heparan sulfate D-glucosamine 3-O-sulfotransferase 3B1 is a novel regulator of transforming growth factor-beta-mediated epithelial-to-mesenchymal transition and regulated by miR-218 in nonsmall cell lung cancer.
Journal of cancer research and therapeutics - 1 Jan 2018
Zhang Zengli, Jiang Hanyi, Wang Yongsheng, Shi Minhua
Abstract excerpt
BACKGROUND: Due to high metastasis and recurrence rate. Recent studies indicated that epithelial-to-mesenchymal transition (EMT) was involved in the progression and metastasis in cancer. Some reports also indicate that HS3ST3B1 played a role in angiogenesis and the proliferation of cancer cells. In this study, we aim to investigate its role in non-small cell lung cancer (NSCLC) . MATERIALS AND METHODS: All cell...
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