Article
Altered gene expression in dry age-related macular degeneration suggests early loss of choroidal endothelial cells.
Molecular vision - 1 Jan 2013
Whitmore S Scott, Braun Terry A, Skeie Jessica M, Haas Christine M, Sohn Elliott H, Stone Edwin M, Scheetz Todd E, Mullins Robert F
Abstract excerpt
PURPOSE: Age-related macular degeneration (AMD) is a major cause of blindness in developed countries. The molecular pathogenesis of early events in AMD is poorly understood. We investigated differential gene expression in samples of human retinal pigment epithelium (RPE) and choroid from early AMD and control maculas with exon-based arrays. METHODS: Gene expression levels in nine human donor eyes with early AMD...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.