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The transcriptome of peripheral blood mononuclear cells in patients with clinical subtypes of late age-related macular degeneration

15 Aug 2019

Abstract excerpt

Peripheral blood mononuclear cells (PBMCs) are implicated in the pathogenesis of age-related macular degeneration (AMD). We here mapped the global gene transcriptome of PBMCs from patients with different clinical subtypes of late AMD. We sampled fresh venous blood from patients with geographic atrophy (GA) secondary to AMD without choroidal neovascularizations ( n = 19), patients with neovascular AMD without GA (...

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PMID: 31428180
DOI: 10.1186/s12979-019-0160-0

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