Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of the prevalence and prospective clinical impact of the JAK2 V617F mutation in coronary patients.

American journal of hematology - 1 Mar 2014

Muendlein Axel, Gasser Klaus, Kinz Elena, Stark Nicole, Leiherer Andreas, Rein Philipp, Saely Christoph H, Grallert Harald, Peters Annette, Drexel Heinz, Lang Alois H

Abstract excerpt

The JAK2 V617F mutation is not only found in the majority of patients with myeloproliferative neoplasms (MPN), including essential thrombocythemia (ET), but also has been reported in individuals without overt MPN. A close relation of the JAK2 V617F mutation to atherothrombotic events has been described, at least in patients with MPN. The prevalence of the JAK2 V617F mutation and its clinical impact in coronary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Agents
Share to Coronary Angiography

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Artery Disease

Share to Coronary Disease

Share to Janus Kinase 2

Share to Platelet Count

Share to Polycythemia Vera

Share to Thrombocythemia, Essential

Source

Identifiers

PMID: 24265174
DOI: 10.1002/ajh.23632

Genes

JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of the prevalence and prospective clinical impact of the JAK2 V617F mutation in coronary patients.PMID 24265174Read ↗

Occurrence of the JAK2 V617F mutation in patients with peripheral arterial disease.Semantic proximity Read ↗

[Somatic mutation of the V617F JAK2 gene in patients of the cardiovascular diseases].Semantic proximity Read ↗

Clinical correlates of JAK2V617F allele burden in essential thrombocythemia.Semantic proximity Read ↗

Prevalence and Clinical Characteristics of Patients with Ischemic Stroke with <i>JAK2</i> V617F Mutation and Normal Blood CountsSemantic proximity Read ↗

High prevalence of arterial thrombosis in JAK2 mutated essential thrombocythaemia: independence of the V617F allele burden.Semantic proximity Read ↗

Endothelial JAK2V617F mutation leads to thrombosis, vasculopathy, and cardiomyopathy in a murine model of myeloproliferative neoplasmSemantic proximity Read ↗

<i>JAK2</i>V617F mutation in platelets from essential thrombocythemia patients: correlation with clinical features and analysis of STAT5 phosphorylation statusSemantic proximity Read ↗

Is JAK2 V617F mutation more than a diagnostic index? A meta-analysis of clinical outcomes in essential thrombocythemia.Semantic proximity Read ↗

Thromboinflammation in ischemic cerebrovascular patients with the JAK2V617F mutation.Semantic proximity Read ↗

Diagnostic value of JAK2 V617F somatic mutation for myeloproliferative cancer in 49 488 individuals from the general population.Semantic proximity Read ↗

JAK2 allele burden is correlated with a risk of venous but not arterial thrombosis.Semantic proximity Read ↗

Endothelial JAK2V617F mutation leads to thrombosis, vasculopathy, and cardiomyopathy in a murine model of myeloproliferative neoplasm.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.