Article
Routine assessment of on-clopidogrel platelet reactivity and gene polymorphisms in predicting clinical outcome following drug-eluting stent implantation in patients with stable coronary artery disease.
JACC. Cardiovascular interventions - 1 Nov 2013
Viviani Anselmi Chiara, Briguori Carlo, Roncarati Roberta, Papa Laura, Visconti Gabriella, Focaccio Amelia, De Micco Francesca, Latronico Michael V G, Pagnotta Paolo, Condorelli Gianluigi
Abstract excerpt
OBJECTIVES: This study sought to assess the usefulness of clopidogrel-pathway genotyping and on-treatment platelet reactivity (OTR) testing in predicting major adverse cardiac events (MACE) in stable coronary artery disease (CAD) patients receiving drug-eluting stents (DES) under dual antiplatelet (clopidogrel plus aspirin) therapy. BACKGROUND: The role of pharmacogenetics and OTR in predicting MACE-death,...
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