Article
CD24(hi)CD27(+) B cells from patients with allergic asthma have impaired regulatory activity in response to lipopolysaccharide.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Apr 2014
van der Vlugt L E P M, Mlejnek E, Ozir-Fazalalikhan A, Janssen Bonas M, Dijksman T R, Labuda L A, Schot R, Guigas B, Möller G M, Hiemstra P S, Yazdanbakhsh M, Smits H H
Abstract excerpt
BACKGROUND: Regulatory B cells have been identified that strongly reduce allergic and auto-immune inflammation in experimental models by producing IL-10. Recently, several human regulatory B-cell subsets with an impaired function in auto-immunity have been described, but there is no information o...
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