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Article

Leishmania infantum amastigotes trigger a subpopulation of human B cells with an immunoregulatory phenotype.

PLoS neglected tropical diseases - 1 Feb 2015

Andreani Guadalupe, Ouellet Michel, Menasria Rym, Gomez Alejandro Martin, Barat Corinne, Tremblay Michel J

Abstract excerpt

Visceral leishmaniasis is caused by the protozoan parasites Leishmania infantum and Leishmania donovani. This infection is characterized by an uncontrolled parasitization of internal organs which, when left untreated, leads to death. Disease progression is linked with the type of immune response generated and a strong correlation was found between disease progression and serum levels of the immunosuppressive...

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Identifiers

PMID: 25710789
DOI: 10.1371/journal.pntd.0003543
PMCID: PMC4339978

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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