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Article

An exploratory case-only analysis of gene-hazardous air pollutant interactions and the risk of childhood medulloblastoma.

Pediatric blood & cancer - 1 Oct 2012

Lupo Philip J, Lee Laura J, Okcu M Fatih, Bondy Melissa L, Scheurer Michael E

Abstract excerpt

BACKGROUND: There is evidence that exposure to chlorinated solvents may be associated with childhood medulloblastoma and primitive neuroectodermal tumor (M/PNET) risk. Animal models suggest genes related to detoxification and DNA repair are important in the carcinogenicity of these pollutants; however, there have been no human studies assessing the modifying effects of these genotypes on the association between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22389292
DOI: 10.1002/pbc.24105
PMCID: PMC3371277

Genes

OGG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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