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Article

Extensive deamidation at asparagine residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer's disease brain.

Acta neuropathologica communications - 21 Aug 2013

Dan Ayaho, Takahashi Muneaki, Masuda-Suzukake Masami, Kametani Fuyuki, Nonaka Takashi, Kondo Hiromi, Akiyama Haruhiko, Arai Takao, Mann David M A, Saito Yuko, Hatsuta Hiroyuki, Murayama Shigeo, Hasegawa Masato

Abstract excerpt

BACKGROUND: Intracytoplasmic inclusions composed of filamentous tau proteins are defining characteristics of neurodegenerative tauopathies, but it remains unclear why different tau isoforms accumulate in different diseases and how they induce abnormal filamentous structures and pathologies. Two t...

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Identifiers

PMID: 24252707
DOI: 10.1186/2051-5960-1-54
PMCID: PMC3893535

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24252707-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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