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Article

Risk-reducing surgery increases survival in BRCA1/2 mutation carriers unaffected at time of family referral.

Breast cancer research and treatment - 1 Dec 2013

Ingham Sarah L, Sperrin Matthew, Baildam Andrew, Ross Gary L, Clayton Richard, Lalloo Fiona, Buchan Iain, Howell Anthony, Evans D Gareth R

Abstract excerpt

The aim of this study was to establish if risk-reducing surgery (RRS) increases survival among BRCA1/2 carriers without breast/ovarian cancer at the time of family referral. Female BRCA1/2 carriers were identified from the Manchester Genetic Medicine Database. Those patients alive and unaffected...

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Source

Identifiers

PMID: 24249359
DOI: 10.1007/s10549-013-2765-x

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24249359-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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