Article
BRCA1/2 mutation carriers & risk reducing mastectomy: Who undergoes surgery and potential benefits.
American journal of surgery - 1 Jan 2024
Record Sydney M, Thomas Samantha M, Ntowe Koumani, Chiba Akiko, Plichta Jennifer K
Abstract excerpt
BACKGROUND: Risk-reducing mastectomy (RRM) is the most effective breast cancer risk-reduction strategy in BRCA1/2 mutation carriers. We examined factors associated with RRM and its relationship with overall survival (OS). METHODS: Patients aged 18-80y at diagnosis of their BRCA1/2 mutation were selected from our institutional database and stratified by RRM receipt. Differences were tested; unadjusted OS was...
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