Elevated mutagenesis does not explain the increased frequency of antibiotic resistant mutants in starved aging colonies.

Abstract excerpt

The frequency of mutants resistant to the antibiotic rifampicin has been shown to increase in aging (starved), compared to young colonies of Escherichia coli. These increases in resistance frequency occur in the absence of any antibiotic exposure, and similar increases have also been observed in response to additional growth limiting conditions. Understanding the causes of such increases in the frequency of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aging
• Share to Drug Resistance, Bacterial
• Share to Escherichia coli