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Article

Molecular analysis of diffuse intrinsic brainstem gliomas in adults.

Journal of neuro-oncology - 1 Jan 2014

Reyes-Botero German, Giry Marine, Mokhtari Karima, Labussière Marianne, Idbaih Ahmed, Delattre Jean-Yves, Laigle-Donadey Florence, Sanson Marc

Abstract excerpt

Diffuse intrinsic brainstem gliomas (DIBG) account for 1-2 % of adult gliomas. Their biological characteristics are scarcely understood and whether DIBG are biologically different from supratentorial gliomas remains to be established. We analyzed 17 DIBG samples for IDH1 R132H, alpha internexin, p53, and Ki67 expression, and, in a subset with sufficient DNA amount, for IDH1 and histone H3 mutational status,...

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Source

Identifiers

PMID: 24242757
DOI: 10.1007/s11060-013-1312-2

Genes

IDH1
EGFR
MGMT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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