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Article

Metabolic abnormalities and hypoleptinemia in α-synuclein A53T mutant mice.

Neurobiology of aging - 1 May 2014

Rothman Sarah M, Griffioen Kathleen J, Fishbein Kenneth W, Spencer Richard G, Makrogiannis Sokratis, Cong Wei-Na, Martin Bronwen, Mattson Mark P

Abstract excerpt

Parkinson's disease (PD) patients frequently display loss of body fat mass and increased energy expenditure, and several studies have outlined a relationship between these metabolic abnormalities and disease severity, yet energy metabolism is largely unstudied in mouse models of PD. Here we characterize metabolic and physiologic responses to a high calorie diet (HCD) in mice expressing in neurons a mutant form of...

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Identifiers

PMID: 24239384
DOI: 10.1016/j.neurobiolaging.2013.10.088
PMCID: PMC3946232

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SNCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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