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Article

Diet-induced obesity accelerates the onset of terminal phenotypes in α-synuclein transgenic mice.

Journal of neurochemistry - 1 Dec 2014

Rotermund Carola, Truckenmüller Felicia M, Schell Heinrich, Kahle Philipp J

Abstract excerpt

Parkinson's disease (PD) and diabetes belong to the most common neurodegenerative and metabolic syndromes, respectively. Epidemiological links between these two frequent disorders are controversial. The neuropathological hallmarks of PD are protein aggregates composed of amyloid-like fibrillar and serine-129 phosphorylated (pS129) α-synuclein (AS). To study if diet-induced obesity could be an environmental risk...

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PMID: 24995537
DOI: 10.1111/jnc.12813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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