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Article

Sex-specific pleiotropic changes in emotional behavior and alcohol consumption in human α-synuclein A53T transgenic mice during early adulthood.

Journal of neurochemistry - 1 Mar 2024

Kalinichenko Liubov S, Kohl Zacharias, Mühle Christiane, Hassan Zurina, Hahn Agnes, Schmitt Eva-Maria, Macht Kilian, Stoyanov Lyubomir, Moghaddami Schayan, Bilbao Roberto, Eulenburg Volker, Winkler Jürgen, Kornhuber Johannes, Müller Christian P

Abstract excerpt

Point mutations in the α-synuclein coding gene may lead to the development of Parkinson's disease (PD). PD is often accompanied by other psychiatric conditions, such as anxiety, depression, and drug use disorders, which typically emerge in adulthood. Some of these point mutations, such as SNCA and A30T, have been linked to behavioral effects that are not commonly associated with PD, especially regarding alcohol...

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Identifiers

PMID: 38284431
DOI: 10.1111/jnc.16051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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