Article
Association of lymphotoxin alpha polymorphism with type 1 diabetes in a Tunisian population.
Biochemical genetics - 1 Feb 2014
Stayoussef Mouna, Zidi Ines, Mansour Jihen Ben, Moumni Imen, Almawi Wassim Y, Mahjoub Touhami
Abstract excerpt
We investigated the association of the lymphotoxin (LT)-α gene polymorphism +249A/G with type 1 diabetes. The distribution of genotypes of the LT-α +249A/G single nucleotide polymorphism (SNP) was assessed in 115 diabetic patients and 123 normoglycemic control subjects, using PCR-restriction fragment length polymorphism analysis. Among unselected patients, the SNP was significantly associated with increased risk...
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