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Article

Family-based analysis of tumor necrosis factor and lymphotoxin-alpha tag polymorphisms with type 1 diabetes in the population of South Croatia.

Human immunology - 1 Mar 2009

Boraska Vesna, Zeggini Eleftheria, Groves Christopher J, Rayner Nigel W, Skrabić Veselin, Diakite Mahamadou, Rockett Kirk A, Kwiatkowski Dominic, McCarthy Mark I, Zemunik Tatijana

Abstract excerpt

Tumor necrosis factor (TNF) and lymphotoxin-alpha (LTA) are cytokines with a wide range of inflammatory and immunomodulatory activities. Type 1 diabetes is an autoimmune disease characterized by destruction of insulin-producing pancreatic beta cells. The aim of the present study was to evaluate the association of polymorphisms in the TNF/LTA gene region with susceptibility to type 1 diabetes. We investigated 11...

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Source

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Identifiers

PMID: 19167443
DOI: 10.1016/j.humimm.2008.12.010
PMCID: PMC2709221

Genes

LTA
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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