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Article

Four genetic polymorphisms of lymphotoxin-alpha gene and cancer risk: a systematic review and meta-analysis.

PloS one - 1 Jan 2013

Huang Yi, Yu Xi, Wang Lingyan, Zhou Shengjun, Sun Jie, Feng Nan, Nie Sheng, Wu Jingmi, Gao Feng, Fei Bing, Wang Jianyong, Lin Zhiqing, Li Xianru, Xu Leiting, Gao Xiang, Ye Meng, Duan Shiwei

Abstract excerpt

Lymphotoxin-alpha (LTA) is a pro-inflammatory cytokine that plays an important role in the inflammatory and immunologic response. Numerous studies have shown LTA polymorphisms as risk factors for cancers, but the results remain inconclusive. The goal of the present meta-analyses is to establish the associations between cancers and four LTA variants (rs1041981, rs2239704, rs2229094 and rs746868). A total of 30...

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Identifiers

PMID: 24349304
DOI: 10.1371/journal.pone.0082519
PMCID: PMC3861395

Genes

LTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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