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Article

MYC rearranged B-cell neoplasms: Impact of genetics on classification.

Cancer genetics - 1 Oct 2016

Haberl Sabine, Haferlach Torsten, Stengel Anna, Jeromin Sabine, Kern Wolfgang, Haferlach Claudia

Abstract excerpt

A cohort comprising 156 patients with B-cell neoplasms harboring an MYC rearrangement was analyzed with respect to phenotypic presentation, molecular markers (TP53, MYC and ID3) and additional cytogenetic abnormalities (concomitantly occurring BCL2, BCL6 and/or CCND1 rearrangements; double, triple or quadruple hit lymphomas = multiple hit lymphomas). MYC translocations occurred as single hit (only MYC rearranged,...

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Topics

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Share to B-Lymphocytes
Share to Cyclin D1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphoma, B-Cell

Share to Proto-Oncogene Proteins c-bcl-2

Share to Proto-Oncogene Proteins c-bcl-6

Share to Proto-Oncogene Proteins c-myc

Share to Translocation, Genetic

Source

Identifiers

PMID: 27810071
DOI: 10.1016/j.cancergen.2016.08.007

Genes

MYC
BCL2
BCL6
CCND1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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