Article
Clinical and psychological characteristics of the initial cohort of the Dominantly Inherited Alzheimer Network (DIAN).
Neuropsychology - 1 Jan 2014
Storandt Martha, Balota David A, Aschenbrenner Andrew J, Morris John C
Abstract excerpt
OBJECTIVE: The purpose was to describe clinical, cognitive, and personality characteristics at baseline assessment of 249 participants, 19 to 60 years of age, in a multinational longitudinal study of autosomal dominant Alzheimer's disease (ADAD). METHOD: Participants (74% cognitively normal) were from ADAD families with mutations in 1 of 3 genes (APP, PSEN1, or PSEN2). Mixed model analyses, including family as a...
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