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Article

Latency-associated protein Acr1 impairs dendritic cell maturation and functionality: a possible mechanism of immune evasion by Mycobacterium tuberculosis.

The Journal of infectious diseases - 1 May 2014

Siddiqui Kaneez F, Amir Mohammed, Gurram Rama Krishna, Khan Nargis, Arora Ashish, Rajagopal Kammara, Agrewala Javed N

Abstract excerpt

Mycobacterium tuberculosis (M. tuberculosis) in latently infected individuals survives and thwarts the attempts of eradication by the immune system. During latency, Acr1 is predominantly expressed by the bacterium. However, whether M. tuberculosis exploits its Acr1 in impairing the host immunity remains widely unexplored. Hence, currently we have investigated the role of Acr1 in influencing the differentiation...

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PMID: 24218502
DOI: 10.1093/infdis/jit595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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