Article
Innate immune recognition of Mycobacterium tuberculosis.
Clinical & developmental immunology - 1 Jan 2011
Kleinnijenhuis Johanneke, Oosting Marije, Joosten Leo A B, Netea Mihai G, Van Crevel Reinout
Abstract excerpt
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a major health problem, with 10 million new cases diagnosed each year. Innate immunity plays an important role in the host defense against M. tuberculosis, and the first step in this process is recognition of MTB by cells of the innate immune system. Several classes of pattern recognition receptors (PPRs) are involved in the recognition of M....
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