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Article

Innate immune recognition of Mycobacterium tuberculosis.

Clinical & developmental immunology - 1 Jan 2011

Kleinnijenhuis Johanneke, Oosting Marije, Joosten Leo A B, Netea Mihai G, Van Crevel Reinout

Abstract excerpt

Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a major health problem, with 10 million new cases diagnosed each year. Innate immunity plays an important role in the host defense against M. tuberculosis, and the first step in this process is recognition of MTB by cells of the innate immune system. Several classes of pattern recognition receptors (PPRs) are involved in the recognition of M....

Topics

Animals
Genetic Predisposition to Disease
Humans
Immunity, Innate
Mycobacterium tuberculosis
Polymorphism, Genetic
Signal Transduction
Tuberculosis

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 21603213
DOI: 10.1155/2011/405310
PMCID: PMC3095423

Genes

NOD2
TLR2
TLR4
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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