Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mycobacterium tuberculosis directs T helper 2 cell differentiation by inducing interleukin-1β production in dendritic cells.

The Journal of biological chemistry - 28 Sept 2012

Dwivedi Ved Prakash, Bhattacharya Debapriya, Chatterjee Samit, Prasad Durbaka Vijay Raghva, Chattopadhyay Debprasad, Van Kaer Luc, Bishai William R, Das Gobardhan

Abstract excerpt

Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), resides and replicates within phagocytes and persists in susceptible hosts by modulating protective innate immune responses. Furthermore, M. tuberculosis promotes T helper 2 (Th2) immune responses by altering the balance of T cell polarizing cytokines in infected cells. However, cytokines that regulate Th2 cell differentiation during TB...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coculture Techniques
Share to Dendritic Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immune System

Share to Interleukin-1beta

Share to Mycobacterium tuberculosis

Share to Phagocytes

Share to Th2 Cells

Share to Tuberculosis

Source

Open in PubMed Open full text

Identifiers

PMID: 22810226
DOI: 10.1074/jbc.M112.375154
PMCID: PMC3460463

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mycobacterium tuberculosis directs T helper 2 cell differentiation by inducing interleukin-1β production in dendritic cells.PMID 22810226Read ↗

Mycobacterium tuberculosis Virulent Factor ESAT-6 Drives Macrophage Differentiation Toward the Pro-inflammatory M1 Phenotype and Subsequently Switches It to the Anti-inflammatory M2 PhenotypeSemantic proximity Read ↗

Early secretory antigen target of 6-kDa of Mycobacterium tuberculosis inhibits macrophage apoptosis and host defense via TLR2Semantic proximity Read ↗

Mycobacterium tuberculosis TlyA Protein Negatively Regulates T Helper (Th) 1 and Th17 Differentiation and Promotes Tuberculosis Pathogenesis.Semantic proximity Read ↗

Early secretory antigen target of 6-kDa of Mycobacterium tuberculosis inhibits macrophage apoptosis and host defense via TLR2Semantic proximity Read ↗

The immune response in tuberculosis.Semantic proximity Read ↗

Impact of Mycobacterium tuberculosis RD1-locus on human primary dendritic cell immune functions.Semantic proximity Read ↗

Mycobacterium Tuberculosis Infection and Inflammation: what is Beneficial for the Host and for the Bacterium?Semantic proximity Read ↗

Mycobacterium tuberculosis effector PPE36 attenuates host cytokine storm damage via inhibiting macrophage M1 polarization.Semantic proximity Read ↗

T Helper 2 Cytokines Inhibit Autophagic Control of Intracellular Mycobacterium tuberculosisSemantic proximity Read ↗

Mycobacterium tuberculosis RpfB drives Th1-type T cell immunity via a TLR4-dependent activation of dendritic cells.Semantic proximity Read ↗

Advances on the Role and Applications of Interleukin-1 in Tuberculosis.Semantic proximity Read ↗

Human IL-6-Producing B Cells Promote the Differentiation of Monocytes Toward an Anti-Inflammatory CD16⁺CD163⁺CD206⁺PD-L1⁺ Phenotype in Tuberculosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.