Control of Mycobacterium tuberculosis through mammalian Toll-like receptors.

doi:10.1016/s0952-7915(02)00355-2

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Article

Control of Mycobacterium tuberculosis through mammalian Toll-like receptors.

Current opinion in immunology - 1 Aug 2002

Stenger Steffen, Modlin Robert L

Abstract excerpt

An efficient immune response against the intracellular pathogen Mycobacterium tuberculosis is critically dependent on rapid detection of the invader by the innate immune response and the activation of the adaptive immune response. Toll-like receptors (TLRs) contribute to innate immunity by the detection of Mycobacteria-associated molecular patterns and mediating the secretion of antibacterial effector molecules....

Topics

Animals
Antigen Presentation
Antigens, Bacterial
Apoptosis
Dendritic Cells
Drosophila Proteins
Humans
Membrane Glycoproteins
Mice
Mice, Knockout
Models, Immunological
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mycobacterium tuberculosis

Reactive Nitrogen Species

Receptors, Cell Surface

Th1 Cells

Toll-Like Receptors

Tuberculosis

Source

Open in PubMed

Identifiers

PMID: 12088679
DOI: 10.1016/s0952-7915(02)00355-2

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