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Article

Pknox1/Prep1 regulates mitochondrial oxidative phosphorylation components in skeletal muscle.

Molecular and cellular biology - 1 Jan 2014

Kanzleiter Timo, Rath Michaela, Penkov Dmitry, Puchkov Dmytro, Schulz Nadja, Blasi Francesco, Schürmann Annette

Abstract excerpt

The homeodomain transcription factor Prep1 was previously shown to regulate insulin sensitivity. Our aim was to study the specific role of Prep1 for the regulation of energy metabolism in skeletal muscle. Muscle-specific ablation of Prep1 resulted in increased expression of respiratory chain subunits. This finding was consistent with an increase in mitochondrial enzyme activity without affecting mitochondrial...

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Source

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Identifiers

PMID: 24216763
DOI: 10.1128/MCB.01232-13
PMCID: PMC3911294

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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