Article

The Mitochondrial Brown Adipose Tissue Maintenance Factor Nipsnap1 Interfaces Directly with the Beta-Oxidation Protein Machinery

2024-12-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The activation of brown adipose tissue (BAT) is associated with improved metabolic health in humans. We previously identified the mitochondrial protein 4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like 1 (Nipsnap1) as a novel regulatory factor that integrates with lipid metabolism and is critical to sustain the long-term activation of BAT, but the precise mechanis...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9b382b38-63ba-55ad-a0fa-f6b8fca94ebc
DOI: 10.1101/2024.12.29.630678

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Mitochondrial Brown Adipose Tissue Maintenance Factor Nipsnap1 Interfaces Directly with the Beta-Oxidation Protein MachineryDOI 10.1101/2024.12.29.630678Read

Nipsnap1—A Regulatory Factor Required For Long-Term Maintenance of Non-Shivering ThermogenesisSemantic proximity Read

Function and Mechanism of Long Noncoding RNAs in Adipocyte BiologySemantic proximity Read

Single-nucleus RNA sequencing reveals cellular and molecular dynamics of white and brown adipose tissue in a mouse model of type-2 diabetesSemantic proximity Read

Loss of neuronatin promotes "browning" of primary mouse adipocytes while reducing Glut1-mediated glucose disposal.Semantic proximity Read

AQP1- A regulatory factor associated with brown adipose tissue-silencingSemantic proximity Read

The long noncoding RNA Blnc1 orchestrates homeostatic adipose tissue remodeling to preserve metabolic healthSemantic proximity Read

Loss of the alternative calcineurin variant CnAβ1 enhances brown adipocyte differentiation and drives metabolic overactivation through FoxO1 activationSemantic proximity Read

Adipocyte lipin 1 is positively associated with metabolic health in humans and regulates systemic metabolism in miceSemantic proximity Read

Shortcuts to a functional adipose tissue: The role of small non-coding RNAs.Semantic proximity Read

Molecular and cellular regulation of thermogenic fatSemantic proximity Read

Multidimensional Single-Nuclei RNA-Seq Reconstruction of Adipose Tissue Reveals Adipocyte Plasticity Underlying Thermogenic ResponseSemantic proximity Read

Maternal Western-style diet programs skeletal muscle gene expression in lean adolescent Japanese macaque offspringSemantic proximity Read