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Metabolic consequences of PGC-1α dysregulation in adult zebrafish muscle

7 Jun 2022

Abstract excerpt

The peroxisome proliferator-activated receptor γ coactivator 1 α (PGC-1α) is central to the regulation of cellular and mitochondrial energy homeostasis in mammals, but its role in other vertebrates remains unclear. Indeed, previous work suggests extensive structural and functional divergence of PGC-1α in teleosts but this remains to be directly tested. Here, we describe the initial characterization of...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 35670765
DOI: 10.1152/ajpregu.00188.2021

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