Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Eukaryotic rpL10 drives ribosomal rotation.

Nucleic acids research - 1 Feb 2014

Sulima Sergey O, Gülay Suna P, Anjos Margarida, Patchett Stephanie, Meskauskas Arturas, Johnson Arlen W, Dinman Jonathan D

Abstract excerpt

Ribosomes transit between two conformational states, non-rotated and rotated, through the elongation cycle. Here, we present evidence that an internal loop in the essential yeast ribosomal protein rpL10 is a central controller of this process. Mutations in this loop promote opposing effects on the natural equilibrium between these two extreme conformational states. rRNA chemical modification analyses reveals...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allosteric Regulation
Share to Ligands
Share to Peptidyl Transferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Biosynthesis

Share to Ribosomal Proteins

Share to Ribosomes

Share to RNA, Ribosomal

Share to Rotation

Source

Open in PubMed Open full text

Identifiers

PMID: 24214990
DOI: 10.1093/nar/gkt1107
PMCID: PMC3919601

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Eukaryotic rpL10 drives ribosomal rotation.PMID 24214990Read ↗

Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly.Semantic proximity Read ↗

Ribosomes in the balance: structural equilibrium ensures translational fidelity and proper gene expression.Semantic proximity Read ↗

Yeast ribosomal protein L10 helps coordinate tRNA movement through the large subunit.Semantic proximity Read ↗

The ATPase Fap7 Tests the Ability to Carry Out Translocation-like Conformational Changes and Releases Dim1 during 40S Ribosome Maturation.Semantic proximity Read ↗

Mutational characterization and mapping of the 70S ribosome active site.Semantic proximity Read ↗

Ribosomal RNA expansion segments and their role in ribosome biologySemantic proximity Read ↗

Mutational analysis of the ribosomal protein Rpl10 from yeast.Semantic proximity Read ↗

rRNA mutants in the yeast peptidyltransferase center reveal allosteric information networks and mechanisms of drug resistance.Semantic proximity Read ↗

Dominant Rio1 kinase/ATPase catalytic mutant induces trapping of late pre-40S biogenesis factors in 80S-like ribosomes.Semantic proximity Read ↗

Integrity of the P-site is probed during maturation of the 60S ribosomal subunit.Semantic proximity Read ↗

A Novel Mutation in RPL10 (Ribosomal Protein L10) Causes X-Linked Intellectual Disability, Cerebellar Hypoplasia, and Spondylo-Epiphyseal Dysplasia.Semantic proximity Read ↗

A molecular clamp ensures allosteric coordination of peptidyltransfer and ligand binding to the ribosomal A-site.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.