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Article

Cytoplasmic localization and redox cysteine residue of APE1/Ref-1 are associated with its anti-inflammatory activity in cultured endothelial cells.

Molecules and cells - 1 Nov 2013

Park Myoung Soo, Kim Cuk-Seong, Joo Hee Kyoung, Lee Yu Ran, Kang Gun, Kim Soo Jin, Choi Sunga, Lee Sang Do, Park Jin Bong, Jeon Byeong Hwa

Abstract excerpt

Apurinic/apyrimidinic endonuclease1/redox factor-1 (APE1/Ref-1) is a multifunctional protein involved in base excision DNA repair and transcriptional regulation of gene expression. APE1/Ref-1 is mainly localized in the nucleus, but cytoplasmic localization has also been reported. However, the functional role of cytoplasmic APE1/Ref-1 and its redox cysteine residue are still unknown. We investigated the role of...

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Identifiers

PMID: 24213673
DOI: 10.1007/s10059-013-0195-6
PMCID: PMC3887937

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Cytoplasmic localization and redox cysteine residue of APE1/Ref-1 are associated with its anti-inflammatory activity in cultured endothelial cells.PMID 24213673Read ↗

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