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Article

Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1).

Nucleic acids research - 1 Jan 2005

Jackson Elias B, Theriot Corey A, Chattopadhyay Ranajoy, Mitra Sankar, Izumi Tadahide

Abstract excerpt

The mammalian abasic-endonuclease1/redox-factor1 (APE1/Ref1) is an essential protein whose subcellular distribution depends on the cellular physiological status. However, its nuclear localization signals have not been studied in detail. We examined nuclear translocation of APE1, by monitoring enhanced green fluorescent protein (EGFP) fused to APE1. APE1's nuclear localization was significantly decreased by...

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Source

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Identifiers

PMID: 15942031
DOI: 10.1093/nar/gki641
PMCID: PMC1143697

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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