Article
Prefrontal cognitive deficits in mice with altered cerebral cortical GABAergic interneurons.
Behavioural brain research - 1 Feb 2014
Bissonette Gregory B, Bae Mihyun H, Suresh Tejas, Jaffe David E, Powell Elizabeth M
Abstract excerpt
Alterations of inhibitory GABAergic neurons are implicated in multiple psychiatric and neurological disorders, including schizophrenia, autism and epilepsy. In particular, interneuron deficits in prefrontal areas, along with presumed decreased inhibition, have been reported in several human patients. The majority of forebrain GABAergic interneurons arise from a single subcortical source before migrating to their...
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