Article
Evaluation of parasite subpopulations and genetic diversity of the msp1, msp2 and glurp genes during and following artesunate monotherapy treatment of Plasmodium falciparum malaria in Western Cambodia.
Malaria journal - 9 Nov 2013
Gosi Panita, Lanteri Charlotte A, Tyner Stuart D, Se Youry, Lon Chanthap, Spring Michele, Char Mengchuor, Sea Darapiseth, Sriwichai Sabaithip, Surasri Sittidech, Wongarunkochakorn Saowaluk, Pidtana Kingkan, Walsh Douglas S, Fukuda Mark M, Manning Jessica, Saunders David L, Bethell Delia
Abstract excerpt
BACKGROUND: Despite widespread coverage of the emergence of artemisinin resistance, relatively little is known about the parasite populations responsible. The use of PCR genotyping around the highly polymorphic Plasmodium falciparum msp1, msp2 and glurp genes has become well established both to describe variability in alleles within a population of parasites, as well as classify treatment outcome in cases of...
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