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Article

Functional polymorphisms of TLR8 are associated with hepatitis C virus infection.

Immunology - 1 Apr 2014

Wang Chiou-Huey, Eng Hock-Liew, Lin Kuei-Hsiang, Liu Hsiang-Chun, Chang Cheng-Hsien, Lin Tsun-Mei

Abstract excerpt

Chronic hepatitis C virus (HCV) infection is a worldwide threat to public health. Toll-like receptor 8 (TLR8) is critical for eliminating RNA viruses, and variation within the TLR8 gene may alter the function of TLR8 in response to HCV infection. Our previous study demonstrated that the TLR8-129G>C (rs3764879) and TLR8+1G>A (rs3764880) variants were in complete linkage disequilibrium, and that the frequency of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24205871
DOI: 10.1111/imm.12211
PMCID: PMC3956428

Genes

TLR8
TLR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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