Article
Toll-like receptor 8 and 9 polymorphisms in Crimean-Congo hemorrhagic fever.
Microbes and infection - 1 Nov 2010
Engin Aynur, Arslan Serdal, Kizildag Sibel, Oztürk Hasret, Elaldi Nazif, Dökmetas Ilyas, Bakir Mehmet
Abstract excerpt
Crimean-Congo hemorrhagic fever (CCHF) is an acute viral hemorrhagic fever. The clinical course and outcome of the CCHF infection are different in humans. Toll-like receptors (TLRs) are a family of pathogen recognition receptors. TLR8 and TLR9 contribute to the recognition of viruses. We investigated frequency of TLR8 Met1Val, TLR8 -129C/G, TLR9 -1486T/C and TLR9 2458G/A polymorphisms in CCHF patients and healthy...
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