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Article

Obese locus in WNIN/obese rat maps on chromosome 5 upstream of leptin receptor.

PloS one - 1 Jan 2013

Kalashikam Rajender Rao, Battula Kiran Kumar, Kirlampalli Veerababu, Friedman Jeffrey M, Nappanveettil Giridharan

Abstract excerpt

WNIN/Obese (WNIN/Ob) rat a new mutant model of metabolic syndrome was identified in 1996 from an inbred Wistar rat strain, WNIN. So far several papers are published on this model highlighting its physical, biochemical and metabolic traits. WNIN/Ob is leptin resistant with unaltered leptin or its receptor coding sequences--the two well-known candidate genes for obesity. Genotyping analysis of F2 progeny (raised...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24204914
DOI: 10.1371/journal.pone.0077679
PMCID: PMC3804619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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